QTc Interval in Infants Receiving Cisapride
نویسندگان
چکیده
منابع مشابه
QT interval in children and infants receiving cisapride.
OBJECTIVES Life-threatening arrhythmias and prolonged QT interval have been reported in adults and children using cisapride, a medication structurally similar to procainamide. Premature infants have reduced activity of cytochrome p-450, the system responsible for metabolism of cisapride, which could lead to QT prolongation. Therefore, we prospectively studied premature infants and children rece...
متن کاملEffects of cisapride on QTc interval in neonates.
AIM Prospective survey of the effects of cisapride on QTc interval in neonates given cisapride. METHODS QTc interval was determined just before and 2.9 (0.9) days after outset of the treatment in 49 neonates treated with cisapride between 1 August 1995 and 29 February 1996. RESULTS Cisapride significantly increased QTc interval (p = 0.0001), and this was higher when birthweight or gestation...
متن کاملEffects of cisapride on QTc interval in term neonates.
BACKGROUND Cisapride administration for 48 hours has been shown to increase heart rate corrected QT (QTc) interval in preterm neonates. Accumulation of the drug because of liver enzyme immaturity has been suggested to be the reason. If this is correct, a longer survey of QTc interval should disclose an increase even in term neonates. OBJECTIVE A prospective survey of the effects of cisapride ...
متن کاملevaluation of qtc interval in iranian causalities (janbazan) of iran-iraq war receiving maintenance methadone treatment
normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background : methadone is a synthetic opioid, used in treatment of chronic pains. the current study was carried out to evaluate the qtc interval in iranian causalities (janbazan) of iran-iraq war receiving maintenance methadone treatment. methods : in 2010, one hundred war causalities in isfahan who chronically take daily dos...
متن کاملEffects of cisapride on corrected QT interval, heart rate, and rhythm in infants undergoing polysomnography.
OBJECTIVE To evaluate the effects of cisapride, a prokinetic gastrointestinal drug, on the electrocardiographic QT interval, heart rate, and rhythm in infants during routine 8-hour polysomnography. Reported electrocardiogram (ECG) and rhythm disturbances in a small number of patients with the use of cisapride provided the impetus for this prospective study. STUDY DESIGN Two hundred fifty-two ...
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ژورنال
عنوان ژورنال: Journal of Perinatology
سال: 2002
ISSN: 0743-8346,1476-5543
DOI: 10.1038/sj.jp.7210613